Search scope:
排序: Display mode:
Frontiers of Agricultural Science and Engineering 2021, Volume 8, Issue 2,
Keywords: climacteric fruit ripening / phytohormones / TFs / epigenetic modifications
Yinglin JI, Mingyang XU, Aide WANG
Frontiers of Agricultural Science and Engineering Pages 314-334 doi: 10.15302/J-FASE-2021386
Keywords: climacteric fruit ripening phytohormones TFs epigenetic modifications
The genetic regulation of skeletal muscle development: insights from chicken studies
Wen LUO, Bahareldin A. ABDALLA, Qinghua NIE, Xiquan ZHANG
Frontiers of Agricultural Science and Engineering 2017, Volume 4, Issue 3, Pages 295-304 doi: 10.15302/J-FASE-2017159
Keywords: chicken epigenetic modification miRNAs skeletal muscle development SNP transcription factor
Qiong CHEN, Qing YU, Yuhu SONG, Peiyuan Li, Ying CHANG, Zhijun WANG, Lifeng LIU, Wei WU, Jusheng LIN
Frontiers of Medicine 2009, Volume 3, Issue 2, Pages 148-152 doi: 10.1007/s11684-009-0032-7
Keywords: gene X-linked inhibitor of apoptosis protein associated factor-1 (XAF1) promoter transcription regulation
Effect of lanthanum chloride on growth of breast cancer cells and regulation of transcription
Xue LI MM , Ping HE MM , Jie XIA MM , Shiwei SONG BS , Jinhai LU BM , Yunde LIU MM ,
Frontiers of Medicine 2009, Volume 3, Issue 3, Pages 336-340 doi: 10.1007/s11684-009-0053-2
Keywords: proliferation c-met invasion lanthanum chloride
SALL4 maintains self-renewal of porcine pluripotent stem cells through downregulation of OTX2
Ning WANG, Sile WANG, Yaxian WANG, Yuanxing CAI, Fan YANG, Huayan WANG
Frontiers of Agricultural Science and Engineering 2019, Volume 6, Issue 1, Pages 81-92 doi: 10.15302/J-FASE-2017180
Sall4 as one of the spalt family members contains several alternative splicing variants, which are differentially expressed and has a key role in maintaining pluripotent stem cells. However, the molecular features and function of SALL4 have not been well elucidated in porcine induced pluripotent stem cells (piPSCs). In this study, we identified splice variants and found two splicing variants through analysis of the porcine transcriptome data derived from piPSCs. SALL4A was only detected in piPSCs but SALL4B was globally expressed in porcine tissues and piPSCs. The level of SALL4B was significantly reduced when piPSCs differentiation occurred, however, the expression of SALL4A was not affected, indicating that SALL4B may be essential for the maintenance of piPSCs self-renewal. Overexpression of SALL4A and SALL4B in PEF cells could significantly stimulated expression of endogenous pluripotent genes, when SALL4B significantly promoted OCT4 expression. Conversely, SALL4A significantly promoted KLF4 expression. Additionally, both SALL4A and SALL4B could repress promoter activity in a dose-dependent manner. Conversely, OTX2 also negatively regulated SALL4 expression. These observations indicate that a negative feedback regulatory mechanism may exist between SALL4 and OTX2, which is useful for the maintenance of the self-renewal of piPSCs.
Keywords: OTX2 pluripotency pig SALL4 transcription regulation
Fengxia YIN,Hui LIU,Shorgan BOU,Guangpeng LI
Frontiers of Agricultural Science and Engineering 2014, Volume 1, Issue 2, Pages 104-113 doi: 10.15302/J-FASE-2014003
Keywords: nuclear reprogramming somatic cell transcription factors transcriptomics
Role of the forkhead transcription factor FOXO-FOXM1 axis in cancer and drug resistance
Fung Zhao, Eric W.-F. Lam
Frontiers of Medicine 2012, Volume 6, Issue 4, Pages 376-380 doi: 10.1007/s11684-012-0228-0
The forkhead transcription factors FOXO and FOXM1 have pivotal roles in tumorigenesis and in mediatingRecent research shows that the forkhead transcription factor FOXM1 is a direct transcriptional targetAn understanding of the role and regulation of the FOXO-FOXM1 axis will impact directly on our knowledge
Keywords: FOXO3a FOXM1 transcription factor cancer drug resistance tumorigenesis
The MYC transcription factor network: balancing metabolism, proliferation and oncogenesis
Patrick A. Carroll, Brian W. Freie, Haritha Mathsyaraja, Robert N. Eisenman
Frontiers of Medicine 2018, Volume 12, Issue 4, Pages 412-425 doi: 10.1007/s11684-018-0650-z
Transcription factor networks have evolved in order to control, coordinate, and separate, the functions
Moving policy and regulation forward for single-use plastic alternatives
Frontiers of Environmental Science & Engineering 2021, Volume 15, Issue 3, doi: 10.1007/s11783-021-1423-5
Keywords: Single-use plastic alternatives Policy Regulation Sustainable development
Phase transition regulation and caloric effect
Frontiers in Energy 2023, Volume 17, Issue 4, Pages 463-477 doi: 10.1007/s11708-023-0860-1
Keywords: phase transition regulation caloric effect solid state refrigeration
The function and regulation of OTU deubiquitinases
Jiansen Du, Lin Fu, Yingli Sui, Lingqiang Zhang
Frontiers of Medicine 2020, Volume 14, Issue 5, Pages 542-563 doi: 10.1007/s11684-019-0734-4
Keywords: ubiquitin OTU deubiquitinases structure function regulation
Characterization of chromatin accessibility in psoriasis
Frontiers of Medicine 2022, Volume 16, Issue 3, Pages 483-495 doi: 10.1007/s11684-021-0872-3
Keywords: psoriasis ATAC-seq epigenetics transcription factor
Molecular regulation and genetic improvement of seed oil content in
Wei HUA,Jing LIU,Hanzhong WANG
Frontiers of Agricultural Science and Engineering 2016, Volume 3, Issue 3, Pages 186-194 doi: 10.15302/J-FASE-2016107
Keywords: breeding maternal effects oilseed rape QTL
Regulation of exogenous bFGF gene mediated by recombinant adeno-associated virus
Ke SONG, Nianjing RAO, Meiling CHEN, Yingguang CAO
Frontiers of Medicine 2009, Volume 3, Issue 2, Pages 158-163 doi: 10.1007/s11684-009-0042-5
Keywords: tetracycline regulatory system adeno-associated virus basic fibroblast growth factor gene regulation
Title Author Date Type Operation
RECENT ADVANCES IN THE REGULATION OF CLIMACTERIC FRUIT RIPENING: HORMONE, TRANSCRIPTION FACTOR AND EPIGENETIC
Journal Article
RECENT ADVANCES IN THE REGULATION OF CLIMACTERIC FRUIT RIPENING: HORMONE, TRANSCRIPTION FACTOR AND EPIGENETIC
Yinglin JI, Mingyang XU, Aide WANG
Journal Article
The genetic regulation of skeletal muscle development: insights from chicken studies
Wen LUO, Bahareldin A. ABDALLA, Qinghua NIE, Xiquan ZHANG
Journal Article
Cloning of human XAF1 gene promoter and assay of its transcription activity in a variety of cell lines
Qiong CHEN, Qing YU, Yuhu SONG, Peiyuan Li, Ying CHANG, Zhijun WANG, Lifeng LIU, Wei WU, Jusheng LIN
Journal Article
Effect of lanthanum chloride on growth of breast cancer cells and regulation of transcription
Xue LI MM , Ping HE MM , Jie XIA MM , Shiwei SONG BS , Jinhai LU BM , Yunde LIU MM ,
Journal Article
SALL4 maintains self-renewal of porcine pluripotent stem cells through downregulation of OTX2
Ning WANG, Sile WANG, Yaxian WANG, Yuanxing CAI, Fan YANG, Huayan WANG
Journal Article
Oocyte-associated transcription factors in reprogramming after somatic cell nuclear transfer: a review
Fengxia YIN,Hui LIU,Shorgan BOU,Guangpeng LI
Journal Article
Role of the forkhead transcription factor FOXO-FOXM1 axis in cancer and drug resistance
Fung Zhao, Eric W.-F. Lam
Journal Article
The MYC transcription factor network: balancing metabolism, proliferation and oncogenesis
Patrick A. Carroll, Brian W. Freie, Haritha Mathsyaraja, Robert N. Eisenman
Journal Article
The function and regulation of OTU deubiquitinases
Jiansen Du, Lin Fu, Yingli Sui, Lingqiang Zhang
Journal Article
Molecular regulation and genetic improvement of seed oil content in
Wei HUA,Jing LIU,Hanzhong WANG
Journal Article